JUNE 20, 2019

| by T. Giles, P. Sakkas, A. Belkhiri, P. Barrow, I. Kyriazakis, N. Foster

Differential immune response to Eimeria maxima infection in fast and slow growing broiler genotypes

Very little has been reported comparing resistance to coccidiosis in fast or slow growing broilers, the latter of which are becoming more prevalent in the broiler industry. We examined mRNA expression in the intestines of fast and slow growing broilers following Eimeria infection. We show that by day 13 post‐infection (d pi) with 2500 or 7000 oocysts of Eimeria maxima, slower‐growing (Ranger Classic) broilers significantly (P < 0.01) upregulated expression of proinflammatory cyclooxygenase genes (LTB4DH, PTSG1 and PTSG2) above that detected in fast growing (Ross 308) broilers. Expression of CD8α mRNA was downregulated in Ross 308 at day 6d pi ...